Tuesday, October 4, 2016

EurekAlert ::: Neural networks adapt to the presence of a toxic HIV protein


HIV-associated neurocognitive disorders (HAND) afflict approximately half of HIV infected patients.

Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it is a potent neurotoxin that continues to be produced despite treatment with antiretroviral therapy.
Researchers at the University of Minnesota found that Tat altered the activity of networked neurons and that the network adapted to the presence of the toxin. The research article entitled, “HIV-1 Tat-Induced Changes in Synaptically-Driven Network Activity Adapt During Prolonged Exposure” is featured in the journal ‘Current HIV Research‘.
courtesy by Bentham Insight

1 comment:

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