Most Accessed Article: CD8+ T-Cells: Function and Response to HIV Infection

CD8+ T-Cells: Function and Response to HIV Infection Author(s): Naveed Gulzar and Karen F.T. CopelandPages 23-37 (15) Abstract: CD8+ T-cells are a critical component of the cellular immune response and they play an important role in the control of viral infection. During HIV infection, CD8+ T-cells are able to recognize infected cells through an MHC-I dependent process and are able to lyse cells harboring viral infection by the secretion of perforin and granzymes. These cytotoxic T-lymphocytes (CTL) can also eliminate virally infected cells...

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Genome Editing – The Latest Weapon For Combatting HIV

Genome Editing – The Latest Weapon For Combatting HIV HIV is among the most feared viruses that emerged in the last century. Feared it is, because it is complicated for the researchers, let alone the sufferers. Having thousands of brilliant minds working for years and publishing tons of researches in order to find clues to eradicating the HIV completely, the virus has still been very resilient to disappear. Thus far the efforts have...

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EurekAlert ::: Neural networks adapt to the presence of a toxic HIV protein

HIV-associated neurocognitive disorders (HAND) afflict approximately half of HIV infected patients. Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it is a potent neurotoxin that continues to be produced despite treatment with antiretroviral therapy. Researchers at the University of Minnesota found that Tat altered the activity of networked neurons and that the network adapted to the presence...

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New Issue ::: Current Computer Aided-Drug Design, 12 Issue 2

Current Computer-Aided Drug Design aims to publish all the latest developments in drug design based on computational techniques. The field of computer-aided drug design has had extensive impact in the area of drug design. Current Computer-Aided Drug Design is an essential journal for all medicinal chemists who wish to be kept informed and up-to-date with all the latest and important developments in computer-aided methodologies and their applications in drug discovery. Each issue contains a series of timely, in-depth reviews, original...

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Recently Published Issue of the Journal in Current Vascular Pharmacology

Current Vascular Pharmacology publishes clinical and research-based reviews, original research articles, letters, debates, drug clinical trial studies and guest edited issues to update all those concerned with the treatment of vascular disease, bridging the gap between clinical practice and ongoing research. Following are the articles from the journal in Current Vascular Pharmacology, 13 issue 5: Article: Platelet Inhibition...

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New Issue ::: Current HIV Research 14 issue 1

Current HIV Research covers all the latest and outstanding developments of HIV research by publishing original research, review articles and guest edited thematic issues. The novel pioneering work in the basic and clinical fields on all areas of HIV research covers: virus replication and gene expression, HIV assembly, virus-cell interaction, viral pathogenesis, epidemiology and transmission, anti-retroviral therapy and adherence, drug discovery, the latest developments in HIV/AIDS vaccines and animal models, mechanisms and interactions with...

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