Correlates of Patient Retention in HIV Care and Treatment Programs in Nigeria

Author(s): Chinenye Ugoji, Nwanneka Okere, Patrick Dakum, Rukeme Ake-Uzoigwe, Donald Igboelina, Nicaise Ndembi, Ernest Ekong, Manhattan Charurat and William A. BlattnerPages 300-307 (8) Abstract: Background: Long-term retention is a crucial component of HIV care because treatment success can only be measured among retained patients. Understanding determinants of retention will inform retention strategies. We evaluated the correlates of retention...

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Brief Messages to Promote Prevention and Detection of Sexually Transmitted Infections

Author(s): Rocio Garcia-Retamero and Edward T. CokelyPages 408-420 (13) Abstract: We review the results of our research program investigating the effects of brief risk awareness interventions for sexually active young adults⎯the age group most at-risk for sexually transmitted infections (STIs). Our review examines the influence of framed messages, individual differences, and visual aids on key attitudes, behavioral intentions, and health outcomes in three extensive longitudinal studies. Our first study showed that health messages can promote...

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Effects of a Quasi-Randomized Web-Based Intervention on Risk Behaviors and Treatment Seeking Among HIV-Positive Men Who Have Sex With Men in Chengdu, China

Author(s): Guodong Mi, Zunyou Wu, Xiaodong Wang, Cynthia X. Shi, Fei Yu, Tian Li, Linglin Zhang, Jennifer M. McGoogan, Lin Pang, Jie Xu and Keming RouPages 490-496 (7) Abstract: The men who have sex with men (MSM) population in China has experienced a recent increase in HIV incidence. Due to the dual stigma and discrimination towards homosexuality and HIV infection, most MSM living with HIV/AIDS are hard to reach by offline intervention initiatives....

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Perspectives of Genome-Editing Technologies for HIV Therapy

Author(s): Hirotaka Ebina, Peter Gee and Yoshio KoyanagiPages 2-8 (7) Abstract: Background: Current HIV antiretroviral therapies potently suppress virus replication and prevent patients from progressing to AIDS but are unable to completely eliminate HIV due to the existence of dormant viral reservoirs which threaten to reemerge at anytime. Recently, genome-editing technologies that can recognize specific DNA sequences, including viral DNA, are...

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Cellular Antiviral Factors that Target Particle Infectivity of HIV-1

Author(s): Christine GoffinetPages 211-216 (6) Abstract: Background: In the past decade, the identification and characterization of antiviral genes with the ability to interfere with virus replication has established cell-intrinsic innate immunity as a third line of antiviral defense in addition to adaptive and classical innate immunity. Understanding how cellular factors have evolved to inhibit HIV-1 reveals particularly vulnerable points of...

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